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1.
Spinal Cord ; 57(5): 372-379, 2019 May.
Artigo em Inglês | MEDLINE | ID: mdl-30626976

RESUMO

STUDY DESIGN: Descriptive study. OBJECTIVES: To determine the effect of respiratory event rule-set changes on the apnoea hypopnoea index, and diagnostic and severity thresholds in people with acute and chronic spinal cord injury. SETTING: Eleven acute spinal cord injury inpatient hospitals across Australia, New Zealand, Canada and England; community dwelling chronic spinal cord injury patients in their own homes. METHODS: Polysomnography of people with acute (n = 24) and chronic (n = 78) tetraplegia were reanalysed from 1999 American Academy of Sleep Medicine (AASM) respiratory scoring, to 2007 AASM 'alternative' and 2012 AASM respectively. Equivalent cut points for published 1999 AASM sleep disordered breathing severity ranges were calculated using receiver operator curves, and results presented alongside analyses from the able-bodied. RESULTS: In people with tetraplegia, shift from 1999 AASM to 2007 AASM 'alternative' resulted in a 22% lower apnoea hypopnoea index, and to 2012 AASM a 17% lower index. In people with tetraplegia, equivalent cut-points for 1999 AASM severities of 5,15 and 30 were calculated at 2.4, 8.1 and 16.3 for 2007 AASM 'alternative' and 3.2, 10.0 and 21.2 for 2012 AASM. CONCLUSION: Interpreting research, prevalence and clinical polysomnography results conducted over different periods requires knowledge of the relationship between different rule-sets, and appropriate thresholds for diagnosis of disease. SPONSORSHIP: This project was proudly supported by the Traffic Accident Commission (Program grant) and the National Health and Medical Research Council (PhD stipend 616605).


Assuntos
Índice de Gravidade de Doença , Síndromes da Apneia do Sono/classificação , Síndromes da Apneia do Sono/diagnóstico , Traumatismos da Medula Espinal/classificação , Traumatismos da Medula Espinal/diagnóstico , Adolescente , Adulto , Idoso , Apneia/classificação , Apneia/diagnóstico , Apneia/epidemiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Polissonografia/classificação , Polissonografia/métodos , Síndromes da Apneia do Sono/epidemiologia , Traumatismos da Medula Espinal/epidemiologia , Adulto Jovem
2.
IEEE Trans Neural Syst Rehabil Eng ; 26(4): 758-769, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-29641380

RESUMO

Sleep stage classification constitutes an important preliminary exam in the diagnosis of sleep disorders. It is traditionally performed by a sleep expert who assigns to each 30 s of the signal of a sleep stage, based on the visual inspection of signals such as electroencephalograms (EEGs), electrooculograms (EOGs), electrocardiograms, and electromyograms (EMGs). We introduce here the first deep learning approach for sleep stage classification that learns end-to-end without computing spectrograms or extracting handcrafted features, that exploits all multivariate and multimodal polysomnography (PSG) signals (EEG, EMG, and EOG), and that can exploit the temporal context of each 30-s window of data. For each modality, the first layer learns linear spatial filters that exploit the array of sensors to increase the signal-to-noise ratio, and the last layer feeds the learnt representation to a softmax classifier. Our model is compared to alternative automatic approaches based on convolutional networks or decisions trees. Results obtained on 61 publicly available PSG records with up to 20 EEG channels demonstrate that our network architecture yields the state-of-the-art performance. Our study reveals a number of insights on the spatiotemporal distribution of the signal of interest: a good tradeoff for optimal classification performance measured with balanced accuracy is to use 6 EEG with 2 EOG (left and right) and 3 EMG chin channels. Also exploiting 1 min of data before and after each data segment offers the strongest improvement when a limited number of channels are available. As sleep experts, our system exploits the multivariate and multimodal nature of PSG signals in order to deliver the state-of-the-art classification performance with a small computational cost.


Assuntos
Sistemas Computacionais , Aprendizado Profundo , Polissonografia/classificação , Fases do Sono , Algoritmos , Árvores de Decisões , Eletroencefalografia/classificação , Eletroencefalografia/estatística & dados numéricos , Eletromiografia/classificação , Eletromiografia/estatística & dados numéricos , Eletroculografia/classificação , Eletroculografia/estatística & dados numéricos , Sistemas Especialistas , Humanos , Análise Multivariada , Polissonografia/estatística & dados numéricos , Processamento de Sinais Assistido por Computador
4.
Sleep Breath ; 19(4): 1335-41, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26407962

RESUMO

PURPOSE: Continuous positive airway pressure (CPAP) devices can estimate apnea-hypopnea index (AHI) using respiratory event detection algorithms. In 2012, rules for manually scoring respiratory events during sleep were updated to version 2.0. The purpose of the present study was to compare residual AHI determined using the Sleepstyle HC608 CPAP device (HC) with those determined by the new manual scoring (NM) rules during CPAP titration in patients with obstructive sleep apnea (OSA). METHODS: Fifty-seven patients underwent CPAP titration with HC. Correlations were assessed between AHI determined by NM and HC. The AHI, the apnea index (AI), and the hypopnea index (HI) were evaluated separately. RESULTS: The mean AHI as assessed using diagnostic polysomnography (PSG) was 53.9 ± 22.4. During CPAP titration, respiratory events were effectively suppressed (HC-AHI, 4.2 ± 6.0; NM-AHI, 6.0 ± 5.8). Lower HI and AHI were obtained using HC compared to NM (HC-HI, 2.9 ± 3.6 and NM-HI, 5.2 ± 4.2, p < 0.001; HC-AHI, 4.2 ± 6.0 and NM-AHI, 6.0 ± 5.8, p < 0.001). Additionally, HC reported higher AI compared to NM (HC-AI, 1.3 ± 2.8; NM-AI, 0.9 ± 2.2, p = 0.002). NM-AI (ß = 1.017, p < 0.001), NM-HI (ß = -0.599, p < 0.001), and NM-arousal index (ß = -0.058, p = 0.042) were associated with greater differences between HC-AHI and NM-AHI in multivariate regression analysis. CONCLUSIONS: Our findings indicate differences in scoring respiratory events between our CPAP device and new version 2.0 manual scoring and suggest that residual AHI values should be carefully interpreted.


Assuntos
Algoritmos , Pressão Positiva Contínua nas Vias Aéreas/instrumentação , Polissonografia/classificação , Polissonografia/instrumentação , Processamento de Sinais Assistido por Computador/instrumentação , Apneia Obstrutiva do Sono/diagnóstico , Apneia Obstrutiva do Sono/terapia , Adulto , Nível de Alerta , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Sensibilidade e Especificidade , Apneia Obstrutiva do Sono/classificação , Fases do Sono , Estatística como Assunto
6.
Sleep Breath ; 19(2): 489-94, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-24906544

RESUMO

STUDY OBJECTIVES: This study investigated the implications of the revised scoring rules of the American Academy of Sleep Medicine (AASM) in patients with heart failure (HF) with Cheyne-Stokes respiration (CSR). METHODS: Ninety-one patients (NYHA ≥II, LVEF ≤45 %; age 73.6 ± 11.3 years old; 81 male subjects) with documented CSR underwent 8 h of cardiorespiratory polygraphy recordings. Those were analyzed by a single scorer strictly applying the 2007 recommended, 2007 alternative, and the 2012 scoring rules. RESULTS: Compared with the AASM 2007 recommended rules, apnea-hypopnea index (AHI) and hypopnea index (HI) increased significantly when the 2007 alternative and 2012 rules were applied (AHI 34.1 ± 13.5/h vs 37.6 ± 13.2/h vs 38.3 ± 13.2/h, respectively; HI 10.2 ± 9.4/h vs 13.7 ± 10.7/h vs 14.4 ± 11.0/h, respectively; all p < 0.001). Duration of CSR increased significantly with the alternate versus recommended 2007 rules (182.2 ± 117.0 vs 170.1 ± 115.0 min; p ≤ 0.001); there was a significant decrease in CSR duration for the 2012 versus 2007 alternative rules (182.2 ± 117.0 vs 166.7 ± 115.4 min; p ≤ 0.001). CONCLUSION: AHI was higher using the AASM 2012 scoring rules due to a less strict definition of hypopnea. Data on the prognostic effects of CSR in patients with HF and the benefits of treatment are mostly based on the AASM 2007 recommended rules, so differences between these and the newer version need to be taken into account.


Assuntos
Respiração de Cheyne-Stokes/classificação , Respiração de Cheyne-Stokes/diagnóstico , Insuficiência Cardíaca/classificação , Insuficiência Cardíaca/diagnóstico , Polissonografia/classificação , Apneia do Sono Tipo Central/classificação , Apneia do Sono Tipo Central/diagnóstico , Apneia Obstrutiva do Sono/classificação , Apneia Obstrutiva do Sono/diagnóstico , Idoso , Idoso de 80 Anos ou mais , Estudos de Coortes , Feminino , Alemanha , Insuficiência Cardíaca/complicações , Humanos , Masculino , Pessoa de Meia-Idade , Oxigênio/sangue , Polissonografia/métodos , Prognóstico
7.
Sleep Breath ; 19(1): 191-5, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24801137

RESUMO

OBJECTIVES: The aim was to evaluate the inter-rater reliability in scoring sleep stages in two sleep labs in Berlin Germany and Beijing China. METHODS: The subjects consist of polysomnography (PSGs) from 15 subjects in a German sleep laboratory, with 7 mild to moderate sleep apnea hypopnea syndrome (SAHS) patients and 8 healthy controls, and PSGs from 15 narcolepsy patients in a Chinese sleep laboratory. Five experienced technologists including two Chinese and three Germans without common training scored the PSGs following the 2007 AASM manual except the EEG signals included only two EEG leads (C3/A2 and C4/A1). Differences in inter-scorer agreement were analyzed based on epoch-by-epoch comparison by means of Cohen's κ, and quantitative sleep parameters by means of intra-class correlation coefficients. RESULTS: Inter-laboratory epoch-by-epoch agreement comparison between scorers from the two countries yielded a moderate agreement with a mean κ value of 0.57 for controls, 0.58 for SAHS, and 0.54 for narcolepsy. When compared with controls, the inter-scoring agreement is higher for wake and N3 stage scoring in SAHS and N1 and N3 scoring in narcolepsy (p < 0.05). The only sleep stage with lower scoring agreement in both SAHS (κ 0.69 vs. 0.79, p = 0.034) and narcolepsy (0.66 vs 0.79, p = 0.022) was stage REM. Inter-laboratory comparisons showed that the most common combinations of deviating scorings were N1 and N2, N2 and N3, and N1 and wake. A 6.5 % deviating scoring rate of wake and REM and a 13.4 % deviating scoring rate of N1 and REM indicated that inter-laboratory scoring in narcolepsy was about twice as in SAHS and controls confused. This was further confirmed by agreement analysis of quantitative parameters using intra-class correlation coefficients ICC(2,1) indicating REM sleep scoring agreement was lower in narcolepsy than in controls (p < 0.05). CONCLUSION: Low REM stage scoring agreement exists for narcoleptics and SAHS, indicating the necessity to study sleep stage scoring agreement for a specific sleep disorder. Intensive training is needed for the scoring of sleep in international multiple center studies to improve the scoring agreement.


Assuntos
Comparação Transcultural , Narcolepsia/classificação , Narcolepsia/diagnóstico , Avaliação de Processos e Resultados em Cuidados de Saúde , Polissonografia/classificação , Apneia Obstrutiva do Sono/classificação , Apneia Obstrutiva do Sono/diagnóstico , Fases do Sono , Adulto , Idoso , Berlim , China , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Reprodutibilidade dos Testes
8.
Comput Biol Med ; 43(7): 833-9, 2013 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-23746724

RESUMO

Non-invasive ventilation (NIV), a recognized treatment for chronic hypercapnic respiratory failure, is predominantly applied at night. Nevertheless, the quality of sleep is rarely evaluated due to the required technological complexity. A new technique for automatic sleep staging is here proposed for patients treated by NIV. This new technique only requires signals (airflow and hemoglobin oxygen saturation) available in domiciliary ventilators plus a photo-plethysmogram, a signal already managed by some ventilators. Consequently, electroencephalogram, electrooculogram, electromyogram, and electrocardiogram recordings are not needed. Cardiorespiratory features are extracted from the three selected signals and used as input to a Support Vector Machine (SVM) multi-class classifier. Two different types of sleep scoring were investigated: the first type was used to distinguish three stages (wake, REM sleep and nonREM sleep), and the second type was used to evaluate five stages (wake, REM sleep, N1, N2 and N3 stages). Patient-dependent and patient-independent classifiers were tested comparing the resulting hypnograms with those obtained from visual/manual scoring by a sleep specialist. An average accuracy of 91% (84%) was obtained with three-stage (five-stage) patient-dependent classifiers. With patient-independent classifiers, an average accuracy of 78% (62%) was obtained when three (five) sleep stages were scored. Also if the PPG-based and flow features are left out, a reduction of 4.5% (resp. 5%) in accuracy is observed for the three-stage (resp. five-stage) cases. Our results suggest that long-term sleep evaluation and nocturnal monitoring at home is feasible in patients treated by NIV. Our technique could even be integrated into ventilators.


Assuntos
Ventilação não Invasiva/métodos , Reconhecimento Automatizado de Padrão/métodos , Polissonografia/métodos , Processamento de Sinais Assistido por Computador , Fases do Sono/fisiologia , Idoso , Eletrocardiografia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Polissonografia/classificação , Taxa Respiratória , Estatísticas não Paramétricas , Máquina de Vetores de Suporte
9.
Chest ; 143(2): 539-543, 2013 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-23381319

RESUMO

Obstructive sleep apnea is increasingly recognized as a comorbidity in many medical illnesses. This has resulted in an increasing need for sleep testing, which is not entirely met by the currently available sleep laboratory facilities. Home, or out-of-center, sleep testing is an alternative to in-laboratory studies. However, coding and billing for home studies is not as straightforward as it is for in-laboratory studies. This article reviews the process of coding and billing for sleep studies done in an unattended setting.


Assuntos
Codificação Clínica , Reembolso de Seguro de Saúde , Monitorização Ambulatorial/classificação , Monitorização Ambulatorial/economia , Polissonografia/classificação , Polissonografia/economia , Pressão Positiva Contínua nas Vias Aéreas , Humanos , Monitorização Ambulatorial/métodos , Polissonografia/métodos , Apneia Obstrutiva do Sono/diagnóstico , Apneia Obstrutiva do Sono/terapia
10.
Neuropsychobiology ; 62(4): 250-64, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20829636

RESUMO

BACKGROUND: In 2007, the AASM Manual for the Scoring of Sleep and Associated Events was published by the American Academy of Sleep Medicine (AASM). Concerning the visual classification of sleep stages, these new rules are intended to replace the rules by Rechtschaffen and Kales (R&K). METHODS: We adapted the automatic R&K sleep scoring system Somnolyzer 24 × 7 to comply with the AASM rules and subsequently performed a validation study based on 72 polysomnographies from the Siesta database (56 healthy subjects, 16 patients, 38 females, 34 males, aged 21-86 years). Scorings according to the AASM rules were performed manually by experienced sleep scorers and semi-automatically by the AASM version of the Somnolyzer. Manual scorings and Somnolyzer reviews were performed independently by at least 2 out of 8 experts from 4 sleep centers. RESULTS: In the quality control process, sleep experts corrected 4.8 and 3.7% of the automatically assigned epochs, resulting in a reliability between 2 Somnolyzer-assisted scorings of 99% (Cohen's kappa: 0.99). In contrast, the reliability between the 2 manual scorings was 82% (kappa: 0.76). The agreement between the 2 Somnolyzer-assisted and the 2 visual scorings was between 81% (kappa: 0.75) and 82% (kappa: 0.76). CONCLUSION: The AASM version of the Somnolyzer revealed an agreement between semi-automated and human expert scoring comparable to that published for the R&K version with a validity comparable to that of human experts, but with a reliability close to 1, thereby reducing interrater variability as well as scoring time to a minimum.


Assuntos
Polissonografia/classificação , Polissonografia/métodos , Fases do Sono , Software , Academias e Institutos , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Valores de Referência
11.
J Sleep Res ; 19(1 Pt 2): 238-47, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-19912509

RESUMO

Recently, the new American Academy of Sleep Medicine (AASM) rules and the old Rechtschaffen and Kales (R&K) criteria for sleep scoring have been shown to produce significantly different results in adults. The aim of this study was to describe in detail such differences in a group of normal children. Polysomnographic recordings from 45 healthy children (18 females and 27 males) aged between 3 and 16 years were scored following both systems and the results compared. Several significant differences between the two scoring systems were found: N1 (AASM) was significantly higher than S1 (R&K) while Stages N2 and R (AASM) were significantly smaller than S2 and rapid eye movement (R&K). The Kendall Tau correlation coefficient revealed a relatively low concordance between the two systems for the scoring of number of stage shifts per hour, minutes and percentage of Stage N1/S1, and of a percentage of Stage S2/N2. The significant differences between R&K and AASM scoring systems suggest taking some caution in adopting the new scoring criteria in children; these might be shown to be potentially useful if careful selection of the appropriate indicators derived from this new method is carried out, such as the percentage of N1 and the number of stage shifts, which are measures very sensitive to the occurrence of arousals in the new AASM system.


Assuntos
Polissonografia/classificação , Guias de Prática Clínica como Assunto , Sono/fisiologia , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Medicina do Sono
12.
Sleep ; 32(2): 139-49, 2009 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-19238800

RESUMO

STUDY OBJECTIVE: To investigate differences between visual sleep scoring according to the classification developed by Rechtschaffen and Kales (R&K, 1968) and scoring based on the new guidelines of the American Academy of Sleep Medicine (AASM, 2007). DESIGN: All-night polysomnographic recordings were scored visually according to the R&K and AASM rules by experienced sleep scorers. Descriptive data analysis was used to compare the resulting sleep parameters. PARTICIPANTS: Healthy subjects and patients (38 females and 34 males) aged between 21 and 86 years. INTERVENTIONS: N/A. MEASUREMENT AND RESULTS: While sleep latency and REM latency, total sleep time, and sleep efficiency were not affected by the classification standard, the time (in minutes and in percent of total sleep time) spent in sleep stage 1 (S1/N1), stage 2 (S2/N2) and slow wave sleep (S3+S4/N3) differed significantly between the R&K and the AASM classification. While light and deep sleep increased (S1 vs. N1 [+10.6 min, (+2.8%)]: P<0.01; S3+S4 vs. N3 [+9.1 min (+2.4%)]: P<0.01), stage 2 sleep decreased significantly according to AASM rules (S2 vs. N2 [-20.5 min, (-4.9%)]: P<0.01). Moreover, wake after sleep onset was significantly prolonged by approximately 4 minutes (P<0.01) according to the AASM standard. Interestingly, the effects on stage REM were age-dependent (intercept at 20 years: -7.5 min; slope: 1.6 min for 10-year age increase). No effects of sex and diagnosis were observed. CONCLUSION: The study shows significant and age-dependent differences between sleep parameters derived from conventional visual sleep scorings on the basis of R&K rules and those based on the new AASM rules. Thus, new normative data have to be established for the AASM standard.


Assuntos
Polissonografia/classificação , Guias de Prática Clínica como Assunto , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Transtornos de Ansiedade/diagnóstico , Transtornos de Ansiedade/fisiopatologia , Córtex Cerebral/fisiopatologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Síndrome da Mioclonia Noturna/diagnóstico , Síndrome da Mioclonia Noturna/fisiopatologia , Doença de Parkinson/diagnóstico , Doença de Parkinson/fisiopatologia , Polissonografia/estatística & dados numéricos , Tempo de Reação/fisiologia , Valores de Referência , Reprodutibilidade dos Testes , Fases do Sono/fisiologia , Adulto Jovem
13.
Sleep ; 32(2): 150-7, 2009 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-19238801

RESUMO

STUDY OBJECTIVES: To compare apnea-hypopnea indices (AHIs) derived using 3 standard hypopnea definitions published by the American Academy of Sleep Medicine (AASM); and to examine the impact of hypopnea definition differences on the measured prevalence of obstructive sleep apnea (OSA). DESIGN: Retrospective review of previously scored in-laboratory polysomnography (PSG). SETTING: Two tertiary-hospital clinical sleep laboratories. PATIENTS OR PARTICIPANTS: 328 consecutive patients investigated for OSA during a 3-month period. INTERVENTIONS: N/A. MEASUREMENTS AND RESULTS: AHIs were originally calculated using previous AASM hypopnea scoring criteria (AHI(Chicago)), requiring either >50% airflow reduction or a lesser airflow reduction with associated >3% oxygen desaturation or arousal. AHIs using the "recommended" (AHI(Rec)) and the "alternative" (AHI(Alt)) hypopnea definitions of the AASM Manual for Scoring of Sleep and Associated Events were then derived in separate passes of the previously scored data. In this process, hypopneas that did not satisfy the stricter hypopnea definition criteria were removed. For AHI(Rec), hypopneas were required to have > or =30% airflow reduction and > or =4% desaturation; and for AHI(Alt), hypopneas were required to have > or =50% airflow reduction and > or =3% desaturation or arousal. The median AHI(Rec) was approximately 30% of the median AHI(Chicago), whereas the median AHI(Alt), was approximately 60% of the AHI(Chicago), with large, AHI-dependent, patient-specific differences observed. Equivalent cut-points for AHI(Rec) and AHI(Alt), compared to AHI(Chicago) cut-points of 5, 15, and 30/h were established with receiver operator curves (ROC). These cut-points were also approximately 30% of AHI(Chicago) using AHI(Rec) and 60% of AHI(Chicago) using AHI(Alt). Failure to adjust cut-points for the new criteria would result in approximately 40% of patients previously classifled as positive for OSA using AHI(Chicago) being negative using AHI(Rec) and 25% being negative using AHI(Alt). CONCLUSIONS: This study demonstrates that using different published standard hypopnea definitions leads to marked differences in AHI. These results provide insight to clinicians and researchers in interpreting results obtained using different published standard hypopnea definitions, and they suggest that consideration should be given to revising the current scoring recommendations to include a single standardized hypopnea definition.


Assuntos
Polissonografia/classificação , Guias de Prática Clínica como Assunto , Apneia Obstrutiva do Sono/diagnóstico , Adulto , Comparação Transcultural , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Oxigênio/sangue , Polissonografia/normas , Valores de Referência , Estudos Retrospectivos , Apneia Obstrutiva do Sono/classificação , Apneia Obstrutiva do Sono/epidemiologia , Estados Unidos , Vitória
14.
Sleep ; 31(12): 1737-44, 2008 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-19090330

RESUMO

STUDY OBJECTIVES: Polysomnographic respiratory events in children should be scored using pediatric respiratory rules. However, due to a lack of data on adolescents, recently revised rules allow children aged 13-18 years to be scored by adult or pediatric criteria. To clarify which criteria to use, we describe the evolution of respiratory events with Tanner stage, and we compare events in children aged 13-18 years with the new American Academy of Sleep Medicine adult and pediatric respiratory rules. DESIGN: Cross-sectional SETTING: Academic hospital PARTICIPANTS: Healthy subjects aged 8-18 years recruited for research purposes. INTERVENTIONS: Physical examination to determine Tanner stage, overnight polysomnogram, and determination of sex hormones. RESULTS: Sixty-eight subjects (Tanner 1-5) were studied, mean age [SD] = 13 +/- 3 years, median apnea hypopnea index (AHI)= 0.1 (range: 0-1.2)/h. The median percentages of total sleep time (TST) with SpO2 < 92% were 0.1 (0-4.2)%, and with end-tidal CO2 > 50 torr was 0.1 (0-88.6)%. Thirty-two subjects were aged 13-18 years, (Tanner 3-5). The difference between AHI scored by pediatric (median = 0 [0-0.9]/h) and adult (median = 0 [0 - 0.5]/h) criteria was statistically significant (P = 0.043), but not clinically relevant. CONCLUSIONS: Respiratory events in normal children aged 8-18 years are rare and unrelated to Tanner stage. Adult or pediatric respiratory rules can be used for scoring polysomnograms in asymptomatic subjects approaching adulthood. Further studies are needed in symptomatic children within this age group.


Assuntos
Polissonografia/estatística & dados numéricos , Puberdade/fisiologia , Ventilação Pulmonar/fisiologia , Adolescente , Adulto , Nível de Alerta/fisiologia , Criança , Estudos Transversais , Feminino , Humanos , Masculino , Síndrome da Mioclonia Noturna/diagnóstico , Síndrome da Mioclonia Noturna/fisiopatologia , Polissonografia/classificação , Valores de Referência , Apneia do Sono Tipo Central/diagnóstico , Apneia do Sono Tipo Central/fisiopatologia , Apneia Obstrutiva do Sono/diagnóstico , Apneia Obstrutiva do Sono/fisiopatologia , Fases do Sono/fisiologia
15.
Arch. bronconeumol. (Ed. impr.) ; 44(6): 318-323, jun. 2008. ilus, tab
Artigo em Es | IBECS | ID: ibc-65362

RESUMO

OBJETIVO: La polisomnografía (PSG) nocturna es la técnica diagnóstica de referencia del síndrome de apneas-hipopneas durante el sueño (SAHS) en niños. El objetivo del estudio ha sido evaluar la utilidad diagnóstica de la poligrafía respiratoria (PR) en niños con sospecha clínica de SAHS remitidos a la Unidad de Trastornos Respiratorios del Sueño. PACIENTES Y MÉTODOS: Se estudió a 53 niños remitidos por sospecha clínica de SAHS (29 varones; 54,7%), con una edad media ± desviación estándar de 6,4 ± 2,9 años. A todos ellos se les realizaron historia clínica, exploración física, PR (Edentec®) y PSG nocturna simultáneamente en el laboratorio de sueño. Se realizó el análisis estadístico para comparar ambas técnicas diagnósticas. RESULTADOS: Definiendo el diagnóstico de SAHS como la presencia de un índice de apneas-hipopneas obstructivas (IAHO) igual o mayor de 3 en la PSG y un índice de eventos respiratorios (IER) de 3 o superior en la PR, la coincidencia diagnóstica fue del 84,9%. La diferencia de medias entre el IAHO y el IER no fue significativa (0,7 ± 5,4; p = 0,34). El coeficiente de correlación intraclase entre el IAHO y el IER fue de de 89,4 (intervalo de confianza del 95%, 82,4-93,7; p < 0,001). Para el diagnóstico de SAHS se consideraron los valores de IAHO iguales o mayores de 1; iguales o mayores de 3, e iguales o mayores de 5. Se calcularon las curvas de eficacia diagnóstica para cada uno de ellos y 4,6 resultó ser el mejor IER para los 3 valores de IAHO considerados. Al analizar por estratos de edad, en niños de 6 años o más el mejor IER obtenido para los 3 valores de IAHO considerados fue 2,1. En niños menores de 6 años se obtuvieron los siguientes valores de IER: 3,35 para IAHO de 1 o superior y 5,85 para IAHO de 3 o mayor y de 5 o superior. CONCLUSIONES: La PR realizada en el laboratorio de sueño es un método válido para el diagnóstico de SAHS en niños


OBJECTIVE: Overnight polysomnography (PSG) is the gold standard diagnostic tool for sleep apnea-hypopnea syndrome (SAHS) in children. The aim of the present study was to evaluate the usefulness of diagnostic respiratory polygraphy in children with clinically suspected SAHS referred to our sleep-disordered breathing clinic. PATIENTS AND METHODS: We studied 53 children referred with clinical suspicion of SAHS; 29 (54.7%) were boys and the mean (SD) age was 6.4 (2.9) years. After a medical history was taken and a physical examination performed, patients underwent respiratory polygraphy (Edentec) simultaneously with overnight PSG in the sleep laboratory. The 2 diagnostic tools were compared using statistical analysis. RESULTS: SAHS was defined by an obstructive apneahypopnea index (OAHI) of 3 or more in overnight PSG and a respiratory disturbance index (RDI) of 3 or more in respiratory polygraphy. The rate of diagnostic agreement was 84.9%. The difference between the mean OAHI and RDI values was not significant (0.7 ± 5.4; P=.34). The intraclass correlation coefficient between the OAHI and RDI was 89.4 (95% confidence interval, 82.4-93.7; P<.001). When receiver operating characteristic curves were calculated for the OAHI cutoff points used for the diagnosis of SAHS (³1, ³3, and ³5), the best RDI cutoff for all 3 OAHI values considered was found to be 4.6. When age strata were considered, in children 6 years or older the best RDI cutoff for the 3 OAHI values was 2.1. In children younger than 6 years the best RDI cutoff was 3.35 for OAHI ³1 and 5.85 for OAHI ³3 and ³5. CONCLUSIONS: Respiratory polygraphy in the sleep laboratory is a valid method for the diagnosis of SAHS in children


Assuntos
Humanos , Masculino , Feminino , Criança , Síndromes da Apneia do Sono/diagnóstico , Polissonografia , Transtornos do Sono-Vigília/complicações , Transtornos do Sono-Vigília/diagnóstico , Apneia Obstrutiva do Sono/diagnóstico , Modelos Logísticos , Polissonografia/classificação , Polissonografia/estatística & dados numéricos , Polissonografia/tendências , Distúrbios do Início e da Manutenção do Sono/diagnóstico , Estudos Prospectivos
17.
Clin Neurophysiol ; 113(11): 1826-31, 2002 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-12417238

RESUMO

OBJECTIVES: The aim of this research has been to introduce an automatic method, simple from the mathematical and computational points of view, for the recognition and classification of the A-phases of the cyclic alternating pattern. METHODS: The automatic method was based on the computation of 5 descriptors, which were derived from the EEG signal and were able to provide a meaningful data reduction. Each of them corresponded to a different frequency band. RESULTS: The computation of these descriptors, followed by the introduction of two suitable thresholds and of simple criteria for logical discrimination, provided results which were in good agreement with those obtained with visual analysis. The method was versatile and could be applied to the study of other important microstructure phenomena by means of very small adaptations. CONCLUSIONS: The simplicity of the method leads to a better understanding and a more precise definition of the visual criteria for the recognition and classification of the microstructure phenomena.


Assuntos
Polissonografia/classificação , Sono/fisiologia , Adulto , Ritmo alfa , Nível de Alerta/fisiologia , Eletroencefalografia , Processamento Eletrônico de Dados , Humanos , Masculino , Cadeias de Markov , Polissonografia/métodos
18.
O.R.L.-DIPS ; 29(3): 108-118, mayo 2002. ilus, tab
Artigo em Es | IBECS | ID: ibc-17819

RESUMO

En los pacientes con apnea del sueño se emplean múltiples métodos para estudiar la estructura anatómica de la vía aérea superior. El problema es que no existe acuerdo sobre qué medidas de las VAS son las más importantes; cómo valorar las regiones que producen la obstrucción y qué técnica emplear. Frente al TC de una hélice, que proporcionaban una imagen por cada giro de 360º, aparece un nuevo sistema que ofrece hasta cuatro imágenes por vuelta, el TC LightSpeed, que además es hasta 6 veces más rápido que los mejores TC ofreciendo así imágenes de mayor calidad. El objetivo de este trabajo es estudiar la utilidad de el TC LightSpeed en el diagnóstico del síndrome de apnea obstructiva del sueño (AU)


Assuntos
Adulto , Idoso , Feminino , Masculino , Pessoa de Meia-Idade , Humanos , Síndromes da Apneia do Sono/diagnóstico , Faringe/fisiopatologia , Faringe , Polissonografia/métodos , Endoscopia , Tomografia Computadorizada de Emissão/métodos , Fases do Sono , Índice de Massa Corporal , Grupos Controle , Meios de Contraste/análise , Obstrução das Vias Respiratórias/complicações , Obstrução das Vias Respiratórias/diagnóstico , Gravação em Vídeo/instrumentação , Síndromes da Apneia do Sono/fisiopatologia , Polissonografia/classificação , Polissonografia/instrumentação , Polissonografia/tendências
19.
O.R.L.-DIPS ; 27(3): 103-109, sept. 2000. ilus
Artigo em Es | IBECS | ID: ibc-5864

RESUMO

Se hace un estudio de la roncopatía crónica, así como del Síndrome de apnea obstructiva del sueño en la infancia, considerando los aspectos epidemiológicos, etiopatogénicos, sintomatología, complicaciones, diagnóstico y tratamiento tanto médico, como instrumental y quirúrgico (AU)


Assuntos
Feminino , Pré-Escolar , Masculino , Humanos , Síndromes da Apneia do Sono/epidemiologia , Síndromes da Apneia do Sono/etiologia , Síndromes da Apneia do Sono/complicações , Síndromes da Apneia do Sono/diagnóstico , Síndromes da Apneia do Sono/cirurgia , Ronco/cirurgia , Ronco/complicações , Ronco/diagnóstico , Ronco/epidemiologia , Ronco/etiologia , Sistema Respiratório/anormalidades , Sistema Respiratório/cirurgia , Sistema Respiratório/patologia , Anamnese/métodos , Tonsila Faríngea/cirurgia , Tonsila Faríngea/patologia , Anormalidades Craniofaciais/cirurgia , Anormalidades Craniofaciais/complicações , Anormalidades Craniofaciais/patologia , Traqueotomia/métodos , Obstrução Nasal/cirurgia , Obstrução Nasal/complicações , Obstrução Nasal/congênito , Obstrução Nasal/epidemiologia , Obstrução Nasal/etiologia , Obstrução Nasal/patologia , Anormalidades Craniofaciais/cirurgia , Anormalidades Craniofaciais/complicações , Anormalidades Craniofaciais/diagnóstico , Anormalidades Craniofaciais/etiologia , Anormalidades Craniofaciais/epidemiologia , Sistema Nervoso/anormalidades , Sistema Nervoso/patologia , Obesidade/complicações , Obesidade/epidemiologia , Obesidade/fisiopatologia , Tonsila Palatina/anormalidades , Tonsila Palatina/cirurgia , Tonsila Palatina/patologia , Mídia Audiovisual , Microscopia de Vídeo/métodos , Polissonografia/classificação , Polissonografia/métodos , Cavidade Nasal/anormalidades , Cavidade Nasal/cirurgia , Cavidade Nasal/patologia , Adenoidectomia/métodos , Rinorreia de Líquido Cefalorraquidiano/cirurgia , Rinorreia de Líquido Cefalorraquidiano/complicações , Rinorreia de Líquido Cefalorraquidiano/epidemiologia , Rinorreia de Líquido Cefalorraquidiano/patologia
20.
Vigilia sueño ; 12(1): 47-49, ene. 2000.
Artigo em Es | IBECS | ID: ibc-26570

RESUMO

La formación del personal técnico para la realización de estudio de sueño es un aspecto básico de la Medicina del sueño. Uno de los aspectos a discutir es si dicha formación debe realizarse de forma específica y dirigida monográficamente a los estudios de sueño o debe ser más amplia e incluir otros aspectos de electrofisiología como una formación en Electroencefalografía, Potenciales Evocados o en funcionalismo respiratorio o cardíaco básico. Otro aspecto discutible es si el personal técnico en sueño debe dedicarse sólo a realizar estudios de sueño o debe compaginar su actividad con otras funciones del servicio donde esté ubicado el laboratorio, con lo que la formación que reciba el técnico deberá adecuarse a su entorno de trabajo. Hay una tendencia a rentabilizar al máximo la formación y el trabajo del personal hospitalario que tiende a que la formación sea amplia y que la persona sea lo más polivalente posible. Ello no es necesariamente malo: un técnico capaz de hacer un buen EEG o potenciales evocados realizará un excelente polisomnograma, porque está habituado a trabajar en condiciones técnicas difíciles. Por otro lado, si el personal es polivalente y bien formado puede suplir en el momento necesario a cualquiera de las otros técnicos del laboratorio. La duración de la formación específica en sueño no debería ser inferior a seis meses, sobre todo si se incluye la labor de estadiaje del sueño. Sería ideal un período de un año en total, incluyendo una formación general en electrofisiología y otra específica en sueño. Aunque es práctica habitual en tres cuartas partes de los laboratorios españoles que las pruebas las realicen ATS, esto no ocurre en todas partes y no debería ser una condición indispensable. Hay un consenso generalizado en la mayoría de laboratorios de sueño en que sería ideal la existencia de una formación reglada y reconocida oficialmente mediante una acreditación a nivel de toda España de “Técnico en Polisomnografía”.Otra posibilidad a considerar también sería la de una formación reglada de “Técnico en Electrofisología Neurológica” o “Técnico en Neurofisiología” que incluyera una formación adicional en estudios de sueño (AU)


Assuntos
Adulto , Feminino , Masculino , Pessoa de Meia-Idade , Humanos , Polissonografia/instrumentação , Polissonografia/métodos , Polissonografia/normas , Sono/fisiologia , Pessoal de Laboratório/educação , Eletrofisiologia/educação , Eletrofisiologia/normas , Eletrofisiologia/métodos , Polissonografia/classificação , Pessoal de Laboratório/legislação & jurisprudência , Pessoal de Laboratório/normas , Pessoal de Laboratório/organização & administração
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